Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152052 | 0.77 | TSHR (0.48) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL8759742 | 0.76 | MAPT (0.39) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL11294601 | 0.75 | TDP1 (0.55) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL596168 | 0.75 | MAPT (0.62) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL19511923 | 0.75 | MAPT (0.62) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL10902894 | 0.74 | TDP1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL1192919 | 0.74 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL6949538 | 0.73 | MAPT (0.50) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL16139485 | 0.73 | TXNRD1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1TSHR | |
| SCHEMBL3243151 | 0.73 | MAPT (0.60) | MEN1KMT2AALDH1A1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088184-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | claimed |
| WO-2012088184-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088184-A1 | INTEGRATED PROCESSES FOR THE PREPARATION OF HETEROCYCLIC AROMATIC POLYMER PRECURSORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088182-A2 | 2,4,5-TRIAMINOTHIOPHENOLS AND RELATED COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |