Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16230037 | 0.90 | AHR (0.42) | AHREPHX2GRIA1CACNG8PDE3B | |
| SCHEMBL454535 | 0.81 | AHR (0.49) | AHREPHX2GRIA1CACNG8PDE3B | |
| SCHEMBL31243804 | 0.81 | AHR (0.49) | AHREPHX2GRIA1CACNG8PDE3B | |
| SCHEMBL16479504 | 0.78 | MMP12 (0.50) | PDE3BPDE3APGRGAAPKM | |
| SCHEMBL12049915 | 0.74 | AHR (0.42) | AHREPHX2GRIA1CACNG8PDE3B | |
| SCHEMBL392563 | 0.70 | AHR (0.49) | AHRPDK2 | |
| SCHEMBL30351303 | 0.70 | AHR (0.49) | AHRPDK2 | |
| SCHEMBL16812906 | 0.69 | IDH1 (0.31) | — | |
| SCHEMBL422134 | 0.69 | PDE3B (0.44) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL17264079 | 0.68 | LPL (0.48) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |