Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 17/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 15/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953943 | 0.90 | PI4KA (0.59) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9954217 | 0.88 | PI4KA (0.56) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL10288740 | 0.88 | PI4KA (0.53) | PI4KAPIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9953643 | 0.84 | PI4KA (0.55) | PI4KAPIK3CG | |
| SCHEMBL9954049 | 0.83 | PI4KA (0.53) | PI4KAPIK3CG | |
| SCHEMBL9955619 | 0.83 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9954365 | 0.81 | PI4KA (0.70) | PI4KAPIK3CGPIK3CA | |
| SCHEMBL9953679 | 0.80 | PI4KA (0.51) | PI4KAPIK3CG | |
| SCHEMBL10288780 | 0.80 | PI4KA (0.52) | PI4KAPIK3CG | |
| SCHEMBL10288787 | 0.80 | PI4KA (0.50) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |