Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 5/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954425 | 0.90 | ALPL (0.61) | ALPLGAASMN1; SMN2CCR4PIK3CA | |
| SCHEMBL9955197 | 0.90 | ALPL (0.66) | ALPLGAASMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL9953749 | 0.87 | ALPL (0.67) | ALPLKMT2ASMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL9953632 | 0.85 | ALPL (0.66) | ALPLKMT2ASMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL9953304 | 0.85 | ALPL (0.71) | ALPLKMT2ASMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL10289041 | 0.85 | ALPL (0.62) | ALPLGAASMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL9953892 | 0.85 | ALPL (0.60) | ALPLGAASMN1; SMN2PIK3CAPIK3CD | |
| SCHEMBL798423 | 0.85 | ALPL (0.76) | ALPLGAAKMT2APIK3CAPIK3CD | |
| SCHEMBL9954198 | 0.85 | ALPL (0.62) | ALPLKMT2APIK3CAPIK3CDPIK3CB | |
| SCHEMBL9953720 | 0.85 | ALPL (0.62) | ALPLPIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |