Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.66 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 4/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953304 | 0.90 | ALPL (0.71) | ALPLSLC22A12KMT2ALMNAMAPT | |
| SCHEMBL9952780 | 0.88 | ALPL (0.68) | ALPLKMT2ALMNAALDH1A1HTT | |
| SCHEMBL9953749 | 0.87 | ALPL (0.67) | ALPLKMT2ALMNAALDH1A1PIK3CD | |
| SCHEMBL9954994 | 0.86 | ALPL (0.66) | ALPLPIK3CDPIK3R1PIK3CAPIK3CB | |
| SCHEMBL798326 | 0.86 | ALPL (0.69) | ALPLKMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL10277379 | 0.86 | ALPL (0.69) | ALPLLMNAALDH1A1HTTPIK3CD | |
| SCHEMBL9953673 | 0.85 | ALPL (0.65) | ALPLKMT2APIK3CDPIK3R1PIK3CA | |
| SCHEMBL798423 | 0.85 | ALPL (0.76) | ALPLKMT2ALMNAALDH1A1PIK3CD | |
| SCHEMBL9954198 | 0.85 | ALPL (0.62) | ALPLKMT2APIK3CDPIK3R1PIK3CA | |
| SCHEMBL9954845 | 0.85 | ALPL (0.67) | ALPLKMT2ALMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |