Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | PNP | P00491 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.30 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31337206 | 0.86 | DGAT1 (0.39) | DGAT1MEN1KMT2AL3MBTL1 | |
| SCHEMBL12289557 | 0.85 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL27250977 | 0.85 | DGAT1 (0.41) | DGAT1NSD2NSD3 | |
| SCHEMBL30897298 | 0.85 | DGAT1 (0.41) | DGAT1NSD2NSD3 | |
| SCHEMBL12289551 | 0.82 | DGAT1 (0.35) | DGAT1PNPUSP2TSHREDNRA | |
| SCHEMBL30962569 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL2430057 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL2422457 | 0.81 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL12289528 | 0.81 | DGAT1 (0.34) | DGAT1PNPUSP2TSHREDNRA | |
| SCHEMBL9952885 | 0.80 | DGAT1 (0.33) | DGAT1BRD4MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |