Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123661 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2ASMN1; SMN2PKM | |
| SCHEMBL31337206 | 0.81 | DGAT1 (0.39) | DGAT1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9953866 | 0.80 | DGAT1 (0.36) | DGAT1MEN1KMT2AL3MBTL1BRD4 | |
| SCHEMBL30897298 | 0.80 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL27250977 | 0.80 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL12289528 | 0.78 | DGAT1 (0.34) | DGAT1MEN1KMT2A | |
| SCHEMBL12289557 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL12289551 | 0.78 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL30962569 | 0.77 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL2422457 | 0.76 | DGAT1 (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |