⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2312825 | 0.83 | — | — | |
| SCHEMBL14690901 | 0.81 | KEAP1 (0.34) | — | |
| SCHEMBL17501314 | 0.77 | — | — | |
| SCHEMBL526232 | 0.73 | LIPG (0.39) | — | |
| SCHEMBL336725 | 0.73 | LIPG (0.39) | — | |
| SCHEMBL2940133 | 0.72 | — | — | |
| SCHEMBL486247 | 0.71 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL18952131 | 0.70 | PRSS1 (0.30) | — | |
| SCHEMBL133332 | 0.69 | — | — | |
| SCHEMBL2354652 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250049812-A1 | Compounds that Inhibit Necroptosis and Their Preparation Methods | SHANGHAI INST ORGANIC CHEMISTRY CAS (CN) | 2025-02-13 | — | — | US | disclosed |
| EP-4403557-A1 | COMPOUND THAT INHIBITS PROGRAMMED CELL NECROSIS, AND PREPARATION METHOD THEREFOR | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2024-07-24 | — | — | EP | disclosed |
| EP-3720852-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-14 | — | — | EP | disclosed |
| US-20200308168-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-01 | — | — | US | disclosed |
| US-10439141-B2 | P-type semiconducting polymers and related methods | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2019-10-08 | — | — | US | disclosed |
| US-20190194194-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | Janssen Sciences Ireland Unlimited Company (IE) | 2019-06-27 | — | — | US | disclosed |
| WO-2019110521-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-06-13 | — | — | WO | disclosed |
| US-20190084982-A1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | Janssen Sciences Ireland Unlimited Company (IE) | 2019-03-21 | — | — | US | disclosed |
| EP-2742045-B1 | ANTIBACTERIAL CYCLOPENTA[C]PYRROLE SUBSTITUTED 3,4-DIHYDRO-1H-[1,8]NAPHTHYRIDINONES | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2019-01-23 | — | — | EP | disclosed |
| US-10155759-B2 | Antibacterial cyclopenta[c]pyrrole substituted 3,4-dihydro-1H-[1,8]naphthyridinones | JANSSEN SCIENCES IRELAND UC (IE) | 2018-12-18 | — | — | US | disclosed |
| WO-2011103430-A1 | PYRIDO[4,3-B]INDOLE AND PYRIDO[3,4-B]INDOLE DERIVATIVES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2011-08-25 | — | — | WO | disclosed |
| US-20110034668-A1 | ELECTRONIC DEVICES | XEROX CORPORATION (US) | 2011-02-10 | — | — | US | disclosed |
| EP-1916250-B1 | Electronic devices comprising poly(dithienyl-benzodithiophenes) as semiconductors | XEROX CORP (US) | 2011-01-05 | — | — | EP | disclosed |
| US-7834132-B2 | Electronic devices | XEROX CORPORATION (US) | 2010-11-16 | — | — | US | disclosed |
| US-7820782-B2 | Poly(dithienylbenzo[1,2-b:4,5-b′]dithiophene) polymers | XEROX CORPORATION (US) | 2010-10-26 | — | — | US | disclosed |
| EP-2213692-A1 | Polymer Semiconductors with High Mobility | Xerox Corporation (US) | 2010-08-04 | — | — | EP | disclosed |
| US-20090181509-A1 | POLYMER SEMICONDUCTORS WITH HIGH MOBILITY | XEROX CORPORATION (US) | 2009-07-16 | — | — | US | disclosed |
| US-20080103286-A1 | Poly(dithienylbenzo[1,2-B:4,5-B']dithiophene) polymers | XEROX CORPORATION | 2008-05-01 | — | — | US | disclosed |
| US-20080102559-A1 | Electronic devices | XEROX CORPORATION | 2008-05-01 | — | — | US | disclosed |
| EP-1916250-A1 | Electronic devices comprising poly(dithienyl-benzodithiophenes) as semiconductors | Xerox Corporation (US) | 2008-04-30 | — | — | EP | disclosed |