Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995410 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRADAM17KDM4EMAPT | |
| SCHEMBL995409 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRADAM17KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10276306 | 0.98 | ALDH1A1 (0.38) | ALDH1A1TSHRADAM17KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10276418 | 0.98 | ALDH1A1 (0.38) | ALDH1A1TSHRADAM17KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL14245533 | 0.98 | ALDH1A1 (0.38) | ALDH1A1TSHRADAM17KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL1504655 | 0.98 | ALDH1A1 (0.38) | ALDH1A1TSHRADAM17KDM4EMAPT | |
| SCHEMBL995766 | 0.83 | EPHX2 (0.35) | ALDH1A1ADAM17KDM4EMAPTPOLB | |
| SCHEMBL995768 | 0.83 | EPHX2 (0.35) | ALDH1A1ADAM17KDM4EMAPTPOLB | |
| SCHEMBL10088097 | 0.83 | LMNA (0.38) | MAPT | |
| Hydrochloric Acid SCHEMBL14245074 | 0.82 | EPHX2 (0.35) | ALDH1A1ADAM17KDM4EMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2801568-A1 | Benzene-sulphonamide compounds, method for synthesising and use in medicine and in cosmetics | Galderma Research & Development (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-2448920-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2014-08-13 | — | — | EP | disclosed |
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |