Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953859 | 0.75 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL23363880 | 0.72 | CNR2 (0.37) | ALDH1A1 | |
| SCHEMBL15053030 | 0.72 | CNR2 (0.37) | ALDH1A1 | |
| SCHEMBL29934730 | 0.72 | CNR2 (0.37) | ALDH1A1 | |
| SCHEMBL5783206 | 0.71 | PDE4A (0.37) | ALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL22047869 | 0.71 | CNR2 (0.36) | ALDH1A1 | |
| SCHEMBL15052560 | 0.71 | CNR2 (0.36) | ALDH1A1 | |
| SCHEMBL24845651 | 0.71 | CYP11B1 (0.56) | CYP11B1CYP11B2ADRA2CCYP19A1 | |
| SCHEMBL5779592 | 0.71 | CNR2 (0.36) | ALDH1A1 | |
| SCHEMBL13105206 | 0.69 | CYP11B1 (0.58) | CYP11B1CYP11B2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |