Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KAT7 | O95251 | 5/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.37 |
| ▸ | KAT6B | Q8WYB5 | 4/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31172777 | 0.78 | KAT7 (0.41) | MAPTGAAKAT7KAT6AKAT6B | |
| SCHEMBL15053030 | 0.75 | CNR2 (0.37) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL9954162 | 0.75 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL23363880 | 0.72 | CNR2 (0.37) | MAPTGAACNR2KMT2AALDH1A1 | |
| SCHEMBL29934730 | 0.72 | CNR2 (0.37) | MAPTGAACNR2KMT2AALDH1A1 | |
| SCHEMBL31172576 | 0.71 | HTR2A (0.46) | MAPTKAT7KAT6AKAT6BKAT5 | |
| SCHEMBL5783206 | 0.71 | PDE4A (0.37) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL22047869 | 0.71 | CNR2 (0.36) | MAPTGAACNR2KMT2AALDH1A1 | |
| SCHEMBL5779592 | 0.71 | CNR2 (0.36) | MAPTGAACNR2MEN1KMT2A | |
| SCHEMBL15052560 | 0.71 | CNR2 (0.36) | MAPTGAACNR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |