Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995424 | 1.00 | KDM4E (0.39) | KDM4ESMN1; SMN2HSD11B1CHRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10276162 | 0.98 | KDM4E (0.38) | KDM4ESMN1; SMN2HSD11B1CHRM1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10276157 | 0.98 | KDM4E (0.38) | KDM4ESMN1; SMN2HSD11B1CHRM1ALDH1A1 | |
| SCHEMBL10088097 | 0.86 | LMNA (0.38) | — | |
| SCHEMBL613641 | 0.85 | KDM4E (0.41) | KDM4ESMN1; SMN2HSD11B1CHRM1ALDH1A1 | |
| SCHEMBL18123012 | 0.85 | SLC6A2 (0.36) | — | |
| Hydrochloric Acid SCHEMBL1504844 | 0.80 | KDM4E (0.36) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL997494 | 0.78 | DPP7 (0.47) | — | |
| SCHEMBL997493 | 0.78 | DPP7 (0.47) | — | |
| SCHEMBL998415 | 0.76 | DPP7 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2801568-A1 | Benzene-sulphonamide compounds, method for synthesising and use in medicine and in cosmetics | Galderma Research & Development (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-2448920-B1 | Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine | GALDERMA RES & DEV (FR) | 2014-08-13 | — | — | EP | disclosed |
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |