Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26555109 | 0.84 | CYP3A4 (0.58) | CYP3A4TRPA1TDP1MAPK1TSHR | |
| SCHEMBL3443182 | 0.81 | CYP3A4 (0.49) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL3333505 | 0.79 | CYP3A4 (0.57) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL662710 | 0.77 | CYP3A4 (0.49) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL29642695 | 0.77 | CYP3A4 (0.49) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL11603296 | 0.76 | CYP3A4 (0.53) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL28191046 | 0.76 | CYP3A4 (0.61) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL29373346 | 0.76 | CYP3A4 (0.71) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL77895 | 0.76 | CYP3A4 (0.71) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 | |
| SCHEMBL542827 | 0.75 | CYP3A4 (0.55) | CYP3A4TRPA1TDP1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0627452-B1 | UV-absorbing polyurethanes and polyesters | CIBA GEIGY AG (CH) | 1998-12-09 | — | — | EP | claimed |
| EP-0507727-B1 | Glass coating with improved adhesion and weather resistance | CIBA GEIGY AG (CH) | 1997-01-22 | — | — | EP | claimed |
| EP-0493320-B1 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA GEIGY AG (CH) | 1996-07-31 | — | — | EP | claimed |
| EP-0362145-B1 | Crosslinked siloxane-urethane polymer contact lens | CIBA GEIGY AG (CH) | 1996-01-03 | — | — | EP | claimed |
| US-5480946-A | CONTACT LENSES | CIBA GEIGY CORPORATION (US) | 1996-01-02 | — | — | US | claimed |
| US-5459222-A | UV-absorbing polyurethanes and polyesters | CIBA-GEIGY CORPORATION | 1995-10-17 | — | — | US | claimed |
| US-5426158-A | Interpenetrating polymer network with vinyl polymer | CIBA-GEIGY CORP. (US) | 1995-06-20 | — | — | US | claimed |
| US-5426204-A | Trialkoxysilane with urea, urethane, sulfide or amide linkages | CIBA-GEIGY CORPORATION (US) | 1995-06-20 | — | — | US | claimed |
| EP-0406161-B1 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA GEIGY AG (CH) | 1995-02-22 | — | — | EP | claimed |
| US-5372889-A | Glass coating with improved adhesion and weather resistance | CIBA-GEIGY CORPORATION (US) | 1994-12-13 | — | — | US | claimed |
| EP-0455585-B1 | Unsaturated urea polysiloxanes | CIBA GEIGY AG (CH) | 1994-03-23 | — | — | EP | claimed |
| US-5266715-A | Covalent bonding of a siloxane-urea compound to form crosslinked copolymer | CIBA-GEIGY CORPORATION (US) | 1993-11-30 | — | — | US | claimed |
| EP-0507727-A2 | Glass coating with improved adhesion and weather resistance | CIBA-GEIGY AG (CH) | 1992-10-07 | — | — | EP | claimed |
| EP-0493320-A2 | Fluorine and/or Silicone containing poly(alkylene-oxide)-block copolymer hydrogels and contact lenses thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | claimed |
| US-5115056-A | FLUORINE AND/OR SILICONE CONTAINING POLY(ALKYLENE-OXIDE)-BLOCK COPOLYMERS AND CONTACT LENSES THEREOF | CIBA-GEIGY CORPORATION (US) | 1992-05-19 | — | — | US | claimed |
| EP-0455585-A1 | Unsaturated urea polysiloxanes | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | claimed |
| US-4983702-A | Crosslinked siloxane-urethane polymer contact lens | CIBA-GEIGY CORPORATION (US) | 1991-01-08 | — | — | US | claimed |
| EP-0406161-A2 | Fluorine and/or silicone containing poly(alkylene-oxide)-block copolymers and contact lenses thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | claimed |
| US-4962178-A | 0XYGEN PERMEABLE MEMBRANE | CIBA-GEIGY CORPORATION (US) | 1990-10-09 | — | — | US | claimed |
| EP-0362145-A2 | Crosslinked siloxane-urethane polymer contact lens | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | claimed |