Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9953858 | 0.92 | MEN1 (0.41) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9954787 | 0.89 | MEN1 (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9953908 | 0.89 | TP53 (0.47) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9954899 | 0.87 | SMN1; SMN2 (0.47) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9954475 | 0.87 | MEN1 (0.44) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9953937 | 0.86 | MEN1 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9953429 | 0.86 | TP53 (0.45) | MEN1KMT2AGPR35MAPTLMNA | |
| SCHEMBL9954815 | 0.86 | ACP1 (0.47) | CA12CA1CA2CA9 | |
| SCHEMBL9954468 | 0.86 | MEN1 (0.46) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL9953654 | 0.86 | TP53 (0.42) | CA12CA1CA2CA9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |