Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.49 |
| ▸ | CDC25B | P30305 | 7/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 4/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.48 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.48 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954430 | 0.92 | LMNA (0.47) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL9954862 | 0.90 | LMNA (0.47) | TACR1NT5ELMNASMN1; SMN2SSTR1 | |
| SCHEMBL8741356 | 0.90 | LMNA (0.58) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL14413410 | 0.89 | TACR1 (0.51) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL14413415 | 0.88 | TACR1 (0.52) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL8586688 | 0.87 | LMNA (0.51) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL10260457 | 0.84 | TACR1 (0.49) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL9943829 | 0.83 | TNF (0.47) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL14519962 | 0.83 | PTPN1 (0.52) | TACR1PTPN1CDC25BPTPN2PTPN11 | |
| SCHEMBL8518190 | 0.82 | LMNA (0.56) | TACR1PTPN1CDC25BPTPN2PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655389-A2 | COMPOUNDS | Novartis AG (CH) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085668-A2 | COMPOUNDS | NOVARTIS AG (CH) | 2012-06-28 | — | — | WO | disclosed |