Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 13/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955414 | 0.94 | PI4KA (0.49) | PI4KAPIK3CGDGAT1 | |
| SCHEMBL9952675 | 0.93 | PI4KA (0.53) | PI4KAPIK3CGDGAT1 | |
| SCHEMBL9954462 | 0.82 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9954745 | 0.81 | PI4KA (0.56) | PI4KAPIK3CG | |
| SCHEMBL9953530 | 0.79 | PI4KA (0.68) | PI4KAPIK3CG | |
| SCHEMBL9955784 | 0.76 | PI4KA (0.57) | PI4KAPIK3CG | |
| Lithium SCHEMBL9955796 | 0.76 | PI4KA (0.57) | PI4KAPIK3CG | |
| SCHEMBL9954448 | 0.74 | PI4KA (0.63) | PI4KAPIK3CG | |
| SCHEMBL9954494 | 0.74 | PI4KA (0.63) | PI4KAPIK3CG | |
| SCHEMBL9954652 | 0.74 | PI4KA (0.76) | PI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |