Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954599 | 1.00 | KMT2A (0.56) | KMT2ACYP2C19MAPTKDM4ETDP1 | |
| SCHEMBL11244923 | 0.81 | KMT2A (0.59) | KMT2AMAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL4781017 | 0.80 | KMT2A (0.58) | KMT2AALOX15P2RX3MEN1ESR1 | |
| SCHEMBL11174716 | 0.80 | KMT2A (0.58) | KMT2AMAPTP2RX3ALDH1A1GAA | |
| SCHEMBL4781020 | 0.80 | KMT2A (0.58) | KMT2AALOX15P2RX3MEN1ESR1 | |
| SCHEMBL2086875 | 0.78 | KMT2A (0.56) | KMT2AMAPTHPGDHSD17B10P2RX3 | |
| SCHEMBL2086872 | 0.78 | KMT2A (0.56) | KMT2AMAPTHPGDHSD17B10P2RX3 | |
| SCHEMBL3402743 | 0.77 | KMT2A (0.80) | KMT2AMAPTTDP1ALDH1A1GAA | |
| SCHEMBL2087129 | 0.77 | KMT2A (0.80) | KMT2AMAPTTDP1ALDH1A1GAA | |
| SCHEMBL2087128 | 0.77 | KMT2A (0.80) | KMT2AMAPTTDP1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |