SCHEMBL995469

SCHEMBL995469

CCC(Br)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9396921 0.81 LMNA (0.52)
SCHEMBL8295411 0.75
SCHEMBL922060 0.75
SCHEMBL11276692 0.72
SCHEMBL11276691 0.72
SCHEMBL4725182 0.71
SCHEMBL28988982 0.69
SCHEMBL28813034 0.69
SCHEMBL977350 0.69
SCHEMBL7950753 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164996-A Sesquiterpene lactone scaberol C selenoether derivative, preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164998-A Sesquiterpene lactone scaberol C dithio carbamate derivative and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-118164997-A Sesquiterpene lactone scaberol C thioether derivative, and preparation method and application thereof 沈阳药科大学 2024-06-11 CN claimed
CN-111153910-B Elephantopus scaber seed lactone derivative and preparation method and application thereof 沈阳药科大学 2021-07-30 CN claimed
CN-111153910-A Elephantopus scaber seed lactone derivative and preparation method and application thereof 沈阳药科大学 2020-05-15 CN claimed
US-8710098-B2 Group of amino substituted benzoyl derivatives and their preparation and their use Institute of Medicinal Biotechnology Chinese Academy of Medical Science (CN) 2014-04-29 US claimed
CN-101367749-B A set of mesidino mesitoyl derivant, preparation and application thereof INST MEDICINAL BIOTECHNOLOGY 2013-04-24 CN claimed
US-20100254904-A1 Novel therapeutic delivery systems BRISTOL-MYERS SQUIBB MEDICAL IMAGING, INC. 2010-10-07 US claimed
WO-2010033598-A2 SYSTEM AND METHOD FOR UTILIZING MICROBUBBLES AND LIPOSOMES AS VIRAL SEQUESTERING AGENTS VERUS BIOTECHNOLOGY CORPORATION (US) 2010-03-25 WO claimed
US-20100069814-A1 SYSTEM AND METHOD FOR UTILIZING MICROBUBBLES AND LIPOSOMES AS VIRAL SEQUESTERING AGENTS VERUS BIOTECHNOLOGY CORPORATION 2010-03-18 US claimed
US-5733572-A Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles IMARX PHARMACEUTICAL CORP. (US) 1998-03-31 US claimed
EP-0802788-A1 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER, Evan C (US) 1997-10-29 EP claimed
CN-1137748-A Gas used as local and subcutaneous transmission carrier and microspheres filled with gas precursor IMARX PHARMACEUTICAL CORP (US) 1996-12-11 CN claimed
EP-0740528-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1996-11-06 EP claimed
CN-1125393-A Novel therapeutic delivery systems IMARX PHARMACEUTICAL CORP (US) 1996-06-26 CN claimed
CN-1125389-A Methods of preparing gas and gaseous precursor-filled microspheres IMARX PHARMACEUTICAL CORP (US) 1996-06-26 CN claimed
EP-0712293-A1 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER, Evan C (US) 1996-05-22 EP claimed
WO-1995015118-A1 GAS MICROSPHERES FOR TOPICAL AND SUBCUTANEOUS APPLICATION IMARX PHARMACEUTICAL CORP. (US) 1995-06-08 WO claimed
WO-1994028780-A2 METHODS OF PREPARING GAS AND GASEOUS PRECURSOR-FILLED MICROSPHERES UNGER EVAN C (US) 1994-12-22 WO claimed
WO-1994028874-A1 NOVEL THERAPEUTIC DELIVERY SYSTEMS UNGER EVAN C (US) 1994-12-22 WO claimed