Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15303154 | 0.78 | KCNH2 (0.46) | KCNH2TSHRAKR1C3ALDH1A1KDM4E | |
| SCHEMBL7318930 | 0.77 | ALDH1A1 (0.47) | KCNH2TSHRALDH1A1KDM4EUSP2 | |
| SCHEMBL27521151 | 0.77 | ALDH1A1 (0.47) | KCNH2TSHRALDH1A1KDM4EUSP2 | |
| SCHEMBL18913824 | 0.76 | TSHR (0.69) | KCNH2TSHRALDH1A1KCNJ1 | |
| SCHEMBL13875031 | 0.76 | TSHR (0.55) | KCNH2TSHRALDH1A1KDM4EUSP2 | |
| SCHEMBL2634073 | 0.75 | AKR1C3 (0.49) | KCNH2TSHRAKR1C3ALDH1A1KDM4E | |
| SCHEMBL29059963 | 0.75 | TSHR (0.47) | KCNH2TSHRALDH1A1KDM4EUSP2 | |
| SCHEMBL7943007 | 0.74 | TSHR (0.54) | KCNH2TSHRALDH1A1LMNAKCNJ1 | |
| SCHEMBL3885276 | 0.74 | FDFT1 (0.51) | ENPP2CA12CA1MMP8S1PR1 | |
| Bromide SCHEMBL11237734 | 0.74 | KCNH2 (0.56) | KCNH2TSHRALDH1A1KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074494-B1 | LIPASE STABILIZATION IN DISHWASHING DETERGENTS | HENKEL AG & CO KGAA (DE) | 2018-04-04 | — | — | EP | disclosed |
| EP-2655587-B1 | LIQUID SURFACTANT PREPARATION CONTAINING LIPASE AND PHOSPHONATE | HENKEL AG & CO KGAA (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-3074494-A1 | LIPASE STABILIZATION IN DISHWASHING DETERGENTS | Henkel AG & Co. KGaA (DE) | 2016-10-05 | — | — | EP | disclosed |
| WO-2015078742-A1 | LIPASE STABILIZATION IN DISHWASHING DETERGENTS | HENKEL AG & CO. KGAA (DE) | 2015-06-04 | — | — | WO | disclosed |
| EP-2655587-A1 | LIQUID SURFACTANT PREPARATION CONTAINING LIPASE AND PHOSPHONATE | Henkel AG & Co. KGaA (DE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012084582-A1 | LIQUID SURFACTANT PREPARATION CONTAINING LIPASE AND PHOSPHONATE | HENKEL AG & CO. KGAA (DE) | 2012-06-28 | — | — | WO | disclosed |