Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132068 | 0.94 | TSHR (0.57) | TSHRKCNH2LOXL2KCNJ1IDO1 | |
| SCHEMBL13014394 | 0.88 | TSHR (0.61) | TSHRKCNH2LOXL2KCNJ1IDO1 | |
| SCHEMBL7940937 | 0.81 | GRM8 (0.51) | TSHRKCNH2KCNJ1SIGMAR1 | |
| SCHEMBL5099961 | 0.80 | LOXL2 (0.53) | TSHRKCNH2LOXL2KCNJ1IDO1 | |
| SCHEMBL334475 | 0.79 | TSHR (0.56) | TSHRLOXL2IDO1LMNAALDH1A1 | |
| SCHEMBL9545598 | 0.79 | TSHR (0.72) | TSHRKCNH2LOXL2KCNJ1IDO1 | |
| SCHEMBL1176909 | 0.79 | TSHR (0.56) | TSHRLOXL2IDO1LMNAALDH1A1 | |
| SCHEMBL6455031 | 0.79 | TSHR (0.72) | TSHRKCNH2LOXL2KCNJ1IDO1 | |
| SCHEMBL10879042 | 0.79 | TSHR (0.72) | TSHRKCNH2LOXL2KCNJ1IDO1 | |
| SCHEMBL8186292 | 0.79 | TSHR (0.56) | TSHRLOXL2IDO1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160235870-A1 | MULTIFUNCTIONAL CHELATORS, COMPLEXES, AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2016-08-18 | — | — | US | disclosed |
| WO-2010011367-A2 | BIMODAL LIGANDS WITH MACROCYCLIC AND ACYCLIC BINDING MOIETIES, COMPLEXES AND COMPOSITIONS THEREOF, AND METHODS OF USING | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160235870-A1 | MULTIFUNCTIONAL CHELATORS, COMPLEXES, AND COMPOSITIONS THEREOF, AND METHODS OF USING SAME | FECH, SLC40A1, TFRC | TSHR 3803/4885KCNH2 4384/4885LOXL2 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.