Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336450 | 0.84 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL3342878 | 0.78 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL4201851 | 0.75 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL3337966 | 0.73 | PDE7A (0.73) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL9953957 | 0.73 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL3341796 | 0.73 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL18239972 | 0.72 | HTT (0.67) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL9954834 | 0.72 | CA12 (0.57) | ALDH1A1L3MBTL1RXFP1HTTKMT2A | |
| SCHEMBL9953514 | 0.71 | MEN1 (0.43) | KMT2AMEN1MAPTSMN1; SMN2PDE7A | |
| SCHEMBL9954662 | 0.71 | PI4KA (0.47) | HTTKMT2AMEN1NPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |