Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9954662 | 0.86 | PI4KA (0.47) | MEN1KMT2AATMPDE7ACASP3 | |
| SCHEMBL9954421 | 0.79 | MEN1 (0.51) | MEN1KMT2AATMPDE7AAVPR1A | |
| SCHEMBL9953451 | 0.75 | MAPT (0.44) | MEN1KMT2ALMNAMAPTTP53 | |
| SCHEMBL31540598 | 0.74 | IDO1 (0.47) | MEN1KMT2AIDO1TDO2IDO2 | |
| SCHEMBL26688703 | 0.72 | MEN1 (0.51) | MEN1KMT2AATMPDE7AAVPR1A | |
| SCHEMBL30757281 | 0.72 | MEN1 (0.51) | MEN1KMT2AATMPDE7AAVPR1A | |
| SCHEMBL9954105 | 0.72 | HCAR1 (0.53) | MEN1KMT2APDE7ATDO2IDO2 | |
| SCHEMBL9954915 | 0.71 | PI4KA (0.47) | TDO2IDO2LMNAHCAR1MAPT | |
| SCHEMBL9954987 | 0.71 | ALDH1A1 (0.64) | MEN1KMT2APDE7AMAPTSMN1; SMN2 | |
| SCHEMBL734626 | 0.70 | ALDH1A1 (0.48) | MEN1KMT2AATMLMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012087938-A1 | QUINAZOLINONE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-06-28 | — | — | WO | disclosed |