SCHEMBL9955071

SCHEMBL9955071

CCNc1cc(OS(=O)(=O)O)ccc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.51
CYP3A4 P08684 1/20 0.51
RECQL P46063 1/20 0.51
GAA P10253 3/20 0.38
GLA P06280 1/20 0.38
ALDH1A1 P00352 3/20 0.35
CYP2C9 P11712 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ACHE P22303 1/20 0.34
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
P2RX7 Q99572 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NLRP3 Q96P20 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4128087 0.77 GAA (0.41) GAAGLAACHESMN1; SMN2MEN1
SCHEMBL16985200 0.76 CYP3A4 (0.56) TSHRCYP3A4RECQLGAAALDH1A1
SCHEMBL4135469 0.76 TDP1 (0.47) GAAGLAALDH1A1MAPTSMN1; SMN2
SCHEMBL6660835 0.76 CYP3A4 (0.56) TSHRCYP3A4RECQLALDH1A1MAPT
Sulfuric Acid SCHEMBL3336768 0.76 TSHR (0.83) TSHRCYP3A4RECQLGAAALDH1A1
SCHEMBL6942611 0.73 GAA (0.39) TSHRGAAGLAALDH1A1MAPT
SCHEMBL4127129 0.71 GAA (0.42) TSHRGAAGLAALDH1A1MEN1
SCHEMBL25917721 0.71 TSHR (0.50) TSHRCYP3A4RECQLP2RX7L3MBTL1
SCHEMBL11321224 0.70 CRHR1 (0.34) GAAGLAALDH1A1MAPTSMN1; SMN2
SCHEMBL6689532 0.69 ALDH1A1 (0.41) CYP3A4RECQLGAAGLAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11986547-B2 Cosmetic composition comprising silicone materials DOW SILICONES CORPORATION (US) 2024-05-21 US disclosed
WO-2022256476-A1 ORRIS ROOT EXTRACTS, COMPOSITIONS, AND METHODS FOR SKIN APPLICATIONS ACCESS BUSINESS GROUP INTERNATIONAL LLC (US) 2022-12-08 WO disclosed
US-20200337981-A1 COSMETIC COMPOSITION COMPRISING SILICONE MATERIALS DOW SILICONES CORPORATION 2020-10-29 US disclosed
EP-3727597-A1 COSMETIC COMPOSITION COMPRISING SILICONE MATERIALS Dow Silicones Corporation (US) 2020-10-28 EP disclosed
EP-2654665-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH (DE) 2013-10-30 EP disclosed
WO-2012083906-A2 METHOD FOR DEVELOPING A LIQUID COMPOSITION TO BE APPLIED TO THE SKIN AS A FOAM AND A COMPOSITION THAT CAN BE APPLIED TOPICALLY MIKA PHARMA GESELLSCHAFT FÜR DIE ENTWICKLUNG UND VERMARKTUNG PHARMAZEUTISCHER PRODUKTE MBH (DE) 2012-06-28 WO disclosed