SCHEMBL995523

SCHEMBL995523

O=C(O)c1cccc(C(=O)Oc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.61
MAPT P10636 5/20 0.58
TDP1 Q9NUW8 3/20 0.58
NSD2 O96028 1/20 0.58
MAPK1 P28482 1/20 0.56
ALDH1A1 P00352 3/20 0.54
KMT2A Q03164 4/20 0.53
MEN1 O00255 2/20 0.53
PARP10 Q53GL7 1/20 0.53
NR4A2 P43354 1/20 0.53
ALOX5 P09917 1/20 0.51
ESR1 P03372 2/20 0.50
ESR2 Q92731 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMO O15229 1/20 0.50
PKM P14618 1/20 0.50
LMNA P02545 1/20 0.50
GAA P10253 1/20 0.50
GALR1 P47211 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL6660728 0.96 AKR1C3 (0.58) AKR1C3MAPTTDP1NSD2MAPK1
SCHEMBL28455036 0.96 AKR1C3 (0.58) AKR1C3MAPTTDP1NSD2MAPK1
Terephthalic Acid SCHEMBL10678592 0.94 MAPT (0.57) AKR1C3MAPTTDP1NSD2MAPK1
Isophthalic Acid SCHEMBL2889737 0.94 PARP10 (0.61) AKR1C3MAPTTDP1NSD2MAPK1
SCHEMBL8848151 0.94 LMNA (0.56) AKR1C3MAPTTDP1NSD2MAPK1
SCHEMBL69684 0.94 NSD2 (0.63) AKR1C3MAPTTDP1NSD2MAPK1
SCHEMBL10497239 0.92 AKR1C3 (0.56) AKR1C3MAPTTDP1NSD2MAPK1
SCHEMBL11196204 0.92 AKR1C3 (0.61) AKR1C3MAPTTDP1NSD2MAPK1
SCHEMBL28168705 0.92 NSD2 (0.61) MAPTTDP1NSD2MAPK1ALDH1A1
SCHEMBL8673010 0.92 NSD2 (0.61) MAPTTDP1NSD2MAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0273147-B1 PROCESS FOR THE PRODUCTION OF SUBSTANTIALLY MONOESTER-FREE DIARYL ESTERS OF AROMATIC DICARBOXYLIC ACIDS GENERAL ELECTRIC COMPANY (US) 1992-03-11 EP claimed
EP-0366297-A2 Filled sprayed polyurea elastomers TEXACO DEVELOPMENT CORPORATION (US) 1990-05-02 EP claimed
EP-0273147-A2 Process for the production of substantially monoester-free diaryl esters of aromatic dicarboxylic acids GENERAL ELECTRIC COMPANY (US) 1988-07-06 EP claimed
US-4737569-A Process for the production of substantially monoester-free diaryl esters of aromatic dicarboxylic acids GENERAL ELECTRIC COMPANY (US) 1988-04-12 US claimed
CN-85109215-A Can form polymkeric substance of hydrogel and its production and application 1986-09-10 CN claimed
EP-0044510-B1 PROCESS FOR THE PREPARATION OF DIARYL ESTERS GENERAL ELECTRIC COMPANY (US) 1984-03-07 EP claimed
WO-1982000289-A1 PROCESS FOR THE PREPARATION OF DIARYL ESTERS GEN ELECTRIC (US) 1982-02-04 WO claimed
EP-0044510-A1 Process for the preparation of diaryl esters GENERAL ELECTRIC COMPANY (US) 1982-01-27 EP claimed
US-12359370-B2 Base interlining, methods for their manufacture and application thereof JOHNS MANVILLE (US) 2025-07-15 US disclosed
EP-4574231-A1 FILTER MATERIAL AND METHOD FOR PROVIDING A FILTER MATERIAL Johns Manville Europe GmbH (DE) 2025-06-25 EP disclosed
US-20250196035-A1 Filter Material and Method for Providing a Filter Material JOHNS MANVILLE 2025-06-19 US disclosed
US-12330100-B2 Highly efficient filter medium JOHNS MANVILLE (US) 2025-06-17 US disclosed
CN-115379887-B Sterilizable porous filter media containing nanofibers EMD密理博公司 2025-05-09 CN disclosed
CN-119220001-A Preparation method of double-layer polyethylene film with antibacterial property 桐城市佳升包装有限公司 2024-12-31 CN disclosed
EP-0044510-A1 Process for the preparation of diaryl esters GENERAL ELECTRIC COMPANY (US) 1982-01-27 EP disclosed
US-4296218-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1981-10-20 US disclosed
US-4251649-A COMPRISING A LOW MOLECULAR WEIGHT MODIFIER POLYESTER AND A POLYFUNCTIONAL HYDROXY OR AMINE TEIJIN LIMITED (JP) 1981-02-17 US disclosed
US-4220563-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1980-09-02 US disclosed
US-4137221-A Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation TEIJIN LIMITED (JP) 1979-01-30 US disclosed
US-4055534-A MOLECULAR WEIGHT, DIISOCYANATE HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1977-10-25 US disclosed