⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19187626 | 1.00 | — | — | |
| SCHEMBL171318 | 0.91 | — | — | |
| SCHEMBL4854735 | 0.88 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL10764012 | 0.88 | ALDH1A1 (0.50) | — | |
| SCHEMBL16202951 | 0.88 | ALDH1A1 (0.38) | — | |
| Hydrochloric Acid SCHEMBL26976882 | 0.85 | DNM1 (0.36) | — | |
| SCHEMBL6897108 | 0.84 | — | — | |
| SCHEMBL39985 | 0.84 | — | — | |
| SCHEMBL14616067 | 0.83 | ALDH1A1 (0.54) | — | |
| SCHEMBL996640 | 0.83 | ALDH1A1 (0.68) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3831372-A1 | MITOGUAZONE FOR PREVENTING THE RELAPSE OR THE PROGRESSION OF MULTIPLE SCLEROSIS | Pathologica LLC (US) | 2021-06-09 | — | — | EP | disclosed |
| US-10350178-B2 | Methods and compositions for treatment of demyelinating diseases | PATHOLOGICA LLC (US) | 2019-07-16 | — | — | US | disclosed |
| EP-3473247-A1 | COMPOSITION FOR ORAL DELIVERY COMPRISING MGBG FOR USE IN TREATING MULTIPLE SCLEROSIS | Pathologica LLC (US) | 2019-04-24 | — | — | EP | disclosed |
| CN-104997762-B | Oral delivery drug comprising MGBG and the method for treating disease | 帕萨罗杰卡有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-109432073-A | Purposes of the MGBG in the drug that preparation treats or prevents progressive MS and its progress | 帕萨罗杰卡有限公司 | 2019-03-08 | — | — | CN | disclosed |
| US-20180360783-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF DEMYELINATING DISEASES | PATHOLOGICA LLC | 2018-12-20 | — | — | US | disclosed |
| EP-2453886-B1 | PHARMACEUTICAL FOR ORAL DELIVERY COMPRISING MGBG AND METHODS OF TREATING DISEASE | PATHOLOGICA LLC (US) | 2018-12-12 | — | — | EP | disclosed |
| CN-105163730-B | Methods and compositions for treating demyelinating diseases | 帕萨罗杰卡有限公司 | 2018-10-30 | — | — | CN | disclosed |
| US-10085955-B2 | Methods and compositions for treatment of demyelinating diseases | PATHOLOGICA LLC (US) | 2018-10-02 | — | — | US | disclosed |
| US-10066099-B2 | Polyester-based resin composition, and molded body using the resin composition | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2018-09-04 | — | — | US | disclosed |
| US-6963010-B2 | Anticancer agents; osteoporosis; autoimmune disease | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-11-08 | — | — | US | disclosed |
| US-20050245615-A1 | Composition containing polyamine transport inhibitor and use thereof | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-11-03 | — | — | US | disclosed |
| EP-1262524-B1 | Polyester based resin composition and molded product therefrom | MITSUBISHI GAS CHEMICAL CO (JP) | 2005-08-24 | — | — | EP | disclosed |
| US-20050176828-A1 | Hydrophobic polyamine analogs and methods for their use | MEDIQUEST THERAPEUTICS, INC. (US) | 2005-08-11 | — | — | US | disclosed |
| US-6740376-B2 | POLYAMIDE AND A POLYESTER OR A POLYAMIDE, A POLYESTER AND POLYETHYLENE TEREPHTHALATE; POLYESTER BY CONDENSATION OF A DICARBOXYLIC ACID OR DIOL HAVING A CYCLIC ACETAL SKELETON | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2004-05-25 | — | — | US | disclosed |
| EP-1373185-A2 | HYDROPHOBIC POLYAMINE ANALOGS AND METHODS FOR THEIR USE | Mediquest Therapeutics, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20030187276-A1 | Hydrophobic polyamine analogs and methods for their use | AMINEX THERAPEUTICS, INC. | 2003-10-02 | — | — | US | disclosed |
| US-20030068455-A1 | Polyester based resin composition and molded product therefrom | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2003-04-10 | — | — | US | disclosed |
| EP-1262524-A2 | Polyester based resin composition and molded product therefrom | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2002-12-04 | — | — | EP | disclosed |
| WO-2002053519-A2 | HYDROPHOBIC POLYAMINE ANALOGS AND METHODS FOR THEIR USE | MEDIQUEST THERAPEUTICS, INC. (US) | 2002-07-11 | — | — | WO | disclosed |