Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.73 |
| ▸ | CTSK | P43235 | 5/20 | 0.73 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068894 | 1.00 | CTSS (0.73) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL1068898 | 1.00 | CTSS (0.73) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL16460386 | 0.85 | CTSS (0.64) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL16460387 | 0.85 | CTSS (0.64) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL10094308 | 0.83 | CTSS (0.62) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL18084174 | 0.83 | CTSS (0.62) | CTSSCTSKACEPPARAPPARG | |
| SCHEMBL3573493 | 0.83 | CTSS (0.52) | CTSSCTSKITGB3FOLH1 | |
| SCHEMBL11022657 | 0.83 | CTSS (0.61) | CTSSCTSKACECTSLCTSB | |
| SCHEMBL16119123 | 0.80 | FOLH1 (0.49) | CTSSCTSKFOLH1 | |
| SCHEMBL8308836 | 0.80 | CTSS (0.70) | CTSSCTSKACECTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655322-A1 | PROCESS FOR PREPARING CHIRAL AMINO ACIDS | Diverchim (FR) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085474-A1 | PROCESS FOR PREPARING CHIRAL AMINO ACIDS | DIVERCHIM (FR) | 2012-06-28 | — | — | WO | disclosed |