Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161986 | 0.80 | MAPT (0.45) | MAPT | |
| SCHEMBL8059320 | 0.79 | MAPT (0.34) | MAPT | |
| SCHEMBL25259165 | 0.76 | MAPT (0.32) | MAPT | |
| SCHEMBL9240267 | 0.71 | ALDH1A1 (0.36) | MAPTHTR2AHRH1 | |
| SCHEMBL26724015 | 0.71 | CA1 (0.39) | MAPTHTR2AHRH1 | |
| SCHEMBL18734478 | 0.69 | METAP1 (0.35) | — | |
| SCHEMBL9955958 | 0.68 | MAPT (0.61) | MAPT | |
| SCHEMBL8054703 | 0.67 | CA1 (0.30) | — | |
| SCHEMBL5199761 | 0.67 | METAP1 (0.33) | — | |
| SCHEMBL15717523 | 0.67 | METAP1 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085166-A1 | METABOTROPIC GLUTAMATE RECEPTOR MODULATORS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-06-28 | — | — | WO | disclosed |