SCHEMBL995609

SCHEMBL995609

Cc1ccc(/C=C(/C#N)C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.71
CISD1 Q9NZ45 1/20 0.71
KDM4E B2RXH2 1/20 0.71
SLC16A3 O15427 1/20 0.71
ALDH1A1 P00352 1/20 0.71
CYP3A4 P08684 1/20 0.71
HPGD P15428 1/20 0.71
SLC16A1 P53985 1/20 0.71
GPR35 Q9HC97 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL995610 1.00 EGFR (0.71) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL1792662 1.00 EGFR (0.71) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL15129030 0.91 CISD1 (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL10058489 0.91 CISD1 (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL10046554 0.91 CISD1 (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL10058492 0.91 CISD1 (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL12661978 0.91 CISD1 (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL11941572 0.91 CISD1 (0.59) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL4600830 0.90 EGFR (0.85) EGFRCISD1KDM4ESLC16A3ALDH1A1
SCHEMBL10413058 0.90 EGFR (0.85) EGFRCISD1KDM4ESLC16A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4067367-B1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF LUNAN PHARMACEUTICAL GROUP CORP (CN) 2025-05-28 EP disclosed
US-20230023332-A1 OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF LUNAN PHARMACEUTICAL GROUP CORPORATION (CN) 2023-01-26 US disclosed
EP-4067367-A1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF Lunan Pharmaceutical Group Corporation (CN) 2022-10-05 EP disclosed
WO-2021104391-A1 OLEANANE CINNAMAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 鲁南制药集团股份有限公司 2021-06-03 WO disclosed
EP-2270076-B1 RESIN MOLDED PRODUCT AND POLYMER FILM FUJIFILM CORP (JP) 2018-05-23 EP disclosed
US-9481830-B2 Cholesteric liquid crystal mixture, film, selective reflective plate, laminate, laminated glass FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
EP-2267067-B1 Ultraviolet absorber composition and resin composition stabilized with the absorber composition FUJIFILM CORP (JP) 2015-08-12 EP disclosed
US-20140192286-A1 CHOLESTERIC LIQUID CRYSTAL MIXTURE, FILM, SELECTIVE REFLECTIVE PLATE, LAMINATE, LAMINATED GLASS FUJIFILM CORPORATION (JP) 2014-07-10 US disclosed
US-8541488-B2 Formed resin article and polymer film FUJIFILM CORPORATION (JP) 2013-09-24 US disclosed
US-8044123-B2 Ultraviolet absorber composition and resin composition FUJIFILM CORPORATION (JP) 2011-10-25 US disclosed
EP-2267067-A1 Ultraviolet absorber composition and resin composition stabilized with the absorber composition Fujifilm Corporation (JP) 2010-12-29 EP disclosed
US-20100324181-A1 ULTRAVIOLET ABSORBER COMPOSITION AND RESIN COMPOSITION FUJIFILM CORPORATION (JP) 2010-12-23 US disclosed
US-20100004439-A1 Heterocyclic Compound FUJIFLM CORPORATION (JP) 2010-01-07 US disclosed
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound FUJIFILM CORPORATION (JP) 2009-09-24 US disclosed
US-4645735-A ANTISTATIC FUJI PHOTO FILM CO., LTD. (JP) 1987-02-24 US disclosed
US-4551420-A ULTRAVIOLET RAY ABSORBING POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1985-11-05 US disclosed
US-4464463-A FORMALDEHYDE-GAS SCAVENGER LOADED IN AN ULTRAVIOLET-ABSORBING ACRYLIC POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1984-08-07 US disclosed
US-4464462-A ULTRAVIOLET RAY-ABSORBING ACRYLIC POLYMER LATEX; ANTISTATIC AGENTS FUJI PHOTO FILM CO., LTD. (JP) 1984-08-07 US disclosed
US-4455368-A Silver halide photographic light-sensitive material containing a UV absorbing polymer latex FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
US-4431726-A WHICH IS A POLYMER LATEX FUJI PHOTO FILM CO., LTD. (JP) 1984-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230023332-A1 OLEAN-PHENYLACRYLAMIDE DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF PAOX, ALOX12, PNMT EGFR 4357/4885CISD1 2503/4885KDM4E 991/4885
US-20090239982-A1 Ultraviolet Absorbent and Heterocyclic Compound CYP2A6, CYP2B6, XPO6 EGFR 2374/4885CISD1 2698/4885KDM4E 2273/4885
US-20100004439-A1 Heterocyclic Compound PTGER1, CYP1A1, ALOX12 EGFR 4031/4885CISD1 964/4885KDM4E 2305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.