SCHEMBL9956263

SCHEMBL9956263

COc1c(C(C)(C)C)cc2c(c1-c1ccccc1)C=C(C)C2[Zr](Cl)(Cl)[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28110282 0.89 PDE4B (0.35) PDE4APDE4BPDE4CPDE4D
SCHEMBL14645969 0.83 PDE4B (0.37) PDE4APDE4BPDE4CPDE4D
Hydrochloric Acid SCHEMBL30626389 0.80
SCHEMBL17286312 0.79 PDE4B (0.38) PDE4APDE4BPDE4CPDE4D
SCHEMBL191820 0.79 PDE4A (0.32) PDE4APDE4BPDE4CPDE4D
SCHEMBL17409306 0.78 PDE4B (0.37) PDE4APDE4BPDE4CPDE4D
SCHEMBL17627164 0.78 PDE4A (0.33) PDE4APDE4BPDE4CPDE4D
SCHEMBL21433880 0.78
SCHEMBL17783835 0.78 PDE4B (0.35) PDE4APDE4BPDE4CPDE4D
Hydrochloric Acid SCHEMBL22653349 0.78 PDE4B (0.36) PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10081686-B2 Process for the preparation of copolymers of propylene BOREALIS AG (AT) 2018-09-25 US disclosed
US-9932469-B2 Heterophasic polypropylene polymer Borealis, AG (AT) 2018-04-03 US disclosed
US-20170247480-A1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF PROPYLENE BOREALIS AG (AT) 2017-08-31 US disclosed
EP-3191529-A1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF PROPYLENE Borealis AG (AT) 2017-07-19 EP disclosed
EP-2891667-B1 HETEROPHASIC POLYPROPYLENE POLYMER BOREALIS AG (AT) 2017-03-15 EP disclosed
US-20160333175-A1 HETEROPHASIC POLYPROPYLENE POLYMER BOREALIS AG (AT) 2016-11-17 US disclosed
EP-3019555-A1 HETEROPHASIC COPOLYMER Borealis AG (AT) 2016-05-18 EP disclosed
EP-2824142-B1 Heterophasic copolymer BOREALIS AG (AT) 2016-04-13 EP disclosed
WO-2016038211-A1 PROCESS FOR THE PREPARATION OF COPOLYMERS OF PROPYLENE BOREALIS AG (AT) 2016-03-17 WO disclosed
US-9079985-B2 Bridged metallocene catalysts BOREALIS AG (AT) 2015-07-14 US disclosed
EP-2891667-A1 Heterophasic Polypropylene polymer Borealis AG (AT) 2015-07-08 EP disclosed
WO-2015004251-A1 HETEROPHASIC COPOLYMER BOREALIS AG (AT) 2015-01-15 WO disclosed
EP-2824142-A1 Heterophasic copolymer Borealis AG (AT) 2015-01-14 EP disclosed
US-20140018506-A1 BRIDGED METALLOCENE CATALYSTS BOREALIS AG (AT) 2014-01-16 US disclosed
EP-2655431-A1 BRIDGED METALLOCENE CATALYSTS Borealis AG (AT) 2013-10-30 EP disclosed
WO-2012084961-A1 BRIDGED METALLOCENE CATALYSTS BOREALIS AG (AT) 2012-06-28 WO disclosed