SCHEMBL191820

SCHEMBL191820

COc1c(C(C)(C)C)cc2c(c1-c1ccccc1)C=C(C)C2[Zr](Cl)(Cl)(C1C(C)=Cc2c1cc(C(C)(C)C)c(OC)c2-c1ccccc1)[SiH](C)C

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20609992 0.91
SCHEMBL15808932 0.89
SCHEMBL15808766 0.89
SCHEMBL21815451 0.89
SCHEMBL20165773 0.88
SCHEMBL20165708 0.87
SCHEMBL28415524 0.85
SCHEMBL2595789 0.85 PDE4A (0.32) PDE4APDE4BPDE4CPDE4D
SCHEMBL21433874 0.85
SCHEMBL14645969 0.83 PDE4B (0.37) PDE4APDE4BPDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746336-B1 Polypropylene blend for pressure pipes BOREALIS AG (AT) 2017-04-12 EP claimed
EP-2562215-B1 POLYPROPYLENE BLEND FOR PIPES BOREALIS AG (AT) 2016-03-30 EP claimed
WO-2014095946-A1 POLYPROPYLENE BLEND FOR PRESSURE PIPES BOREALIS AG (AT) 2014-06-26 WO claimed
EP-2746336-A1 Polypropylene blend for pressure pipes Borealis AG (AT) 2014-06-25 EP claimed
WO-2013029699-A1 POLYPROPYLENE BLEND FOR PIPES BOREALIS AG (AT) 2013-03-07 WO claimed
EP-2562215-A1 Polypropylene blend for pipes Borealis AG (AT) 2013-02-27 EP claimed
EP-3562831-B1 CATALYSTS BOREALIS AG (AT) 2021-10-20 EP disclosed
EP-2933276-B1 Improved catalyst system for producing polyethylene copolymers in a high temperature solution polymerization process BOREALIS AG (AT) 2020-12-09 EP disclosed
EP-2487203-B2 Sealing propylene copolymer BOREALIS AG (AT) 2020-11-25 EP disclosed
EP-2978782-B2 PROPYLENE COPOLYMER WITH HIGH IMPACT PROPERTIES BOREALIS AG (AT) 2020-11-18 EP disclosed
EP-3131935-B1 NEW CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2020-06-03 EP disclosed
US-10640685-B2 Multi-layer blown film BOREALIS AG (AT) 2020-05-05 US disclosed
EP-3131934-B1 IMPROVED CATALYST SYSTEM FOR PRODUCING POLYETHYLENE COPOLYMERS IN A HIGH TEMPERATURE SOLUTION POLYMERIZATION PROCESS BOREALIS AG (AT) 2020-01-22 EP disclosed
WO-2011131639-A1 PROPYLENE/1-HEXENE COPOLYMER COMPOSITION WITH LOW SEALING TEMPERATURE BOREALIS AG (AT) 2011-10-27 WO disclosed
WO-2011131637-A1 PROPYLENE/1-HEXENE COPOLYMER COMPOSITION WITH BROAD SEALING WINDOW BOREALIS AG (AT) 2011-10-27 WO disclosed
US-8040790-B2 Low complexity bandwidth efficient carrier frequency offset estimation technique for OFDMA uplink transmissions INDIAN INSTITUTE OF TECHNOLOGY (IN) 2011-10-18 US disclosed
US-7834205-B2 Metallocene compounds Basell Polyolifine GmbH (DE) 2010-11-16 US disclosed
US-20090275712-A1 Metallocene Compounds BASELL POLYOLEFINE GMBH (DE) 2009-11-05 US disclosed
EP-2004664-A1 METALLOCENE COMPOUNDS Basell Polyolefine GmbH (DE) 2008-12-24 EP disclosed
WO-2007116034-A1 METALLOCENE COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2007-10-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275712-A1 Metallocene Compounds MT-CO3, SOD1, MT-CO1 PDE4A 4835/4885PDE4B 4877/4885PDE4C 4862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.