Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 4/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9960003 | 0.94 | FAAH (0.59) | FAAHSCN10ANR3C1PPARGPTGDR2 | |
| SCHEMBL9959139 | 0.89 | FAAH (0.65) | FAAHPLA2G2APTGDR2MEN1NPC1 | |
| SCHEMBL9959066 | 0.87 | FAAH (0.72) | FAAHPLA2G2APTGDR2CNR1MEN1 | |
| SCHEMBL9956255 | 0.85 | FAAH (0.75) | FAAHSCN10APLA2G2APTGDR2MEN1 | |
| SCHEMBL9960034 | 0.85 | FAAH (0.62) | FAAHSCN10APLA2G2AMAPT | |
| SCHEMBL10242361 | 0.85 | FAAH (0.62) | FAAHSCN10APLA2G2ACNR1MAPT | |
| SCHEMBL9959182 | 0.85 | FAAH (0.71) | FAAHSCN10APLA2G2APTGDR2CNR1 | |
| SCHEMBL9959314 | 0.85 | FAAH (0.59) | FAAHSCN10ANR3C1CNR1MAPT | |
| SCHEMBL9958535 | 0.84 | FAAH (0.54) | FAAHSCN10ANR3C1PLA2G2APPARG | |
| SCHEMBL9952599 | 0.84 | FAAH (0.59) | FAAHSCN10APLA2G2APPARGCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088431-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088431-A1 | FAAH INHIBITORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2012-06-28 | — | — | WO | disclosed |