Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1400657 | 0.79 | NPSR1 (0.50) | NPSR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL28992840 | 0.76 | KMT2A (0.48) | NPSR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL12914594 | 0.76 | NPSR1 (0.61) | NPSR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL7859849 | 0.76 | NPSR1 (0.50) | NPSR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL29221819 | 0.74 | HSP90AA1 (0.53) | NPSR1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL31179985 | 0.74 | NPSR1 (0.50) | NPSR1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL10492069 | 0.74 | HTT (0.54) | NPSR1KMT2AALDH1A1NPC1POLB | |
| SCHEMBL28611351 | 0.73 | NPSR1 (0.47) | NPSR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL264029 | 0.72 | NPSR1 (0.56) | NPSR1KMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL27652283 | 0.72 | NAAA (0.57) | NPSR1ALDH1A1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085501-A1 | 8 - SULFO - IMIDAZOTETRAZIN- 4 - ONE COMPOUNDS AND THEIR USE AS ANTICANCER DRUG | PHARMINOX LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |