SCHEMBL1400657

SCHEMBL1400657

CCNC(=O)N(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.50
OPRM1 P35372 1/20 0.49
OPRL1 P41146 1/20 0.49
ALDH1A1 P00352 3/20 0.49
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
GLA P06280 1/20 0.47
TSHR P16473 1/20 0.47
PTGIR P43119 2/20 0.46
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
TP53 P04637 1/20 0.42
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28060972 0.87 HTT (0.50) NPSR1OPRM1OPRL1KMT2AMEN1
SCHEMBL28992840 0.85 KMT2A (0.48) NPSR1ALDH1A1KMT2AMEN1NPC1
SCHEMBL966680 0.82 OPRM1 (0.51) OPRM1OPRL1ALDH1A1KMT2AMEN1
SCHEMBL13543362 0.82 RAB9A (0.50) OPRM1OPRL1ALDH1A1KMT2AMEN1
SCHEMBL10492069 0.82 HTT (0.54) NPSR1ALDH1A1KMT2ANPC1POLB
SCHEMBL31187018 0.81 NPSR1 (0.47) NPSR1OPRM1OPRL1ALDH1A1KMT2A
SCHEMBL965733 0.81 MEN1 (0.67) OPRM1OPRL1ALDH1A1KMT2AMEN1
SCHEMBL9309456 0.81 OPRM1 (0.46) NPSR1OPRM1OPRL1ALDH1A1KMT2A
SCHEMBL4294739 0.81 OPRM1 (0.46) OPRM1OPRL1ALDH1A1KMT2AMEN1
SCHEMBL12914594 0.81 NPSR1 (0.61) NPSR1ALDH1A1KMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3462876-B1 PLANT TREATMENT COMPOSITION CRODA INT PLC (GB) 2021-07-28 EP claimed
EP-3462876-A1 PLANT TREATMENT COMPOSITION Croda International PLC (GB) 2019-04-10 EP claimed
WO-2017208009-A1 PLANT TREATMENT COMPOSITION PLANT IMPACT PLC (GB) 2017-12-07 WO claimed
US-4797419-A AGING RESISTANCE WARNER-LAMBERT COMPANY (US) 1989-01-10 US claimed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-104628659-A Pyrazine-aryle urea derivatives with anti-tumor function and preparation method and application thereof UNIV GUANGXI NORMAL 2015-05-20 CN disclosed
US-7993475-B2 Firing agent for gas generating device NOF CORPORATION (JP) 2011-08-09 US disclosed
EP-1142853-B1 GAS GENERATOR COMPOSITION NOF CORP (JP) 2011-03-02 EP disclosed
US-20100109304-A1 FIRING AGENT FOR GAS GENERATING DEVICE NOF CORPORATION (JP) 2010-05-06 US disclosed
US-20090214911-A1 DIRECT ALCOHOL FUEL CELL FUJIKURA LTD. (JP) 2009-08-27 US disclosed
EP-0735990-A4 COMPOSITE GUN PROPELLANT PROCESSING TECHNIQUE THIOKOL CORP (US) 1997-05-28 EP disclosed
US-5565150-A Energetic materials processing technique THIOKOL CORPORATION (US) 1996-10-15 US disclosed
EP-0735990-A1 COMPOSITE GUN PROPELLANT PROCESSING TECHNIQUE THIOKOL CORPORATION (US) 1996-10-09 EP disclosed
US-5487851-A EXTRUSION MIXTURE OF LACQUERS, CELLULOSE ESTERS AND CELLULOSE NITRATE WITH OXIDIZERS THIOKOL CORPORATION (US) 1996-01-30 US disclosed
WO-1995017358-A1 COMPOSITE GUN PROPELLANT PROCESSING TECHNIQUE THIOKOL CORPORATION (US) 1995-06-29 WO disclosed
US-4893815-A Interactive transector device commercial and military grade ROWAN LARRY (US) 1990-01-16 US disclosed
US-4884809-A Interactive transector device ROWAN LARRY (US) 1989-12-05 US disclosed
US-4797419-A AGING RESISTANCE WARNER-LAMBERT COMPANY (US) 1989-01-10 US disclosed