⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114212 | 0.84 | — | — | |
| SCHEMBL30445119 | 0.82 | CYP1A2 (0.52) | — | |
| SCHEMBL27465211 | 0.71 | — | — | |
| SCHEMBL15315254 | 0.70 | — | — | |
| SCHEMBL29462150 | 0.69 | CPB1 (0.61) | — | |
| SCHEMBL30299391 | 0.67 | — | — | |
| SCHEMBL8312540 | 0.65 | — | — | |
| Arcaine SCHEMBL1737639 | 0.65 | CYP1A2 (0.77) | — | |
| SCHEMBL1736351 | 0.65 | CYP1A2 (0.67) | — | |
| Hydrochloric Acid SCHEMBL538721 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655295-A1 | RADIOIODINATED GUANIDINES | GE Healthcare UK Limited (GB) | 2013-10-30 | — | — | EP | disclosed |
| US-20130272961-A1 | RADIOIODINATED GUANIDINES | GE HEALTHCARE LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| US-20130272961-A1 | RADIOIODINATED GUANIDINES | GE HEALTHCARE LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| US-20130272961-A1 | RADIOIODINATED GUANIDINES | GE HEALTHCARE LIMITED (GB) | 2013-10-17 | — | — | US | disclosed |
| WO-2012084928-A1 | RADIOIODINATED GUANIDINES | GE HEALTHCARE LIMITED (GB) | 2012-06-28 | — | — | WO | disclosed |