Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 4/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786689 | 0.81 | CYP2A6 (0.64) | PIM1CYP2A6LOXL2ABL1BCR | |
| SCHEMBL827247 | 0.78 | CCR1 (0.48) | PIM1GRM5CCR1CCR5CCR8 | |
| SCHEMBL28995952 | 0.76 | ASIC3 (0.60) | PIM1CYP2A6MAPKAPK2LOXL2ABL1 | |
| SCHEMBL1662224 | 0.75 | ASIC3 (0.59) | PIM1CCR1CCR5CCR8 | |
| SCHEMBL15947898 | 0.73 | PIM1 (0.57) | PIM1MAPKAPK2GRM5 | |
| Hydrochloric Acid SCHEMBL15659071 | 0.72 | PIM1 (0.55) | PIM1MAPKAPK2GRM5 | |
| SCHEMBL29387099 | 0.72 | MAPT (0.47) | PIM1MAPKAPK2GRM5ATMPTGS1 | |
| SCHEMBL15578128 | 0.72 | MAPT (0.47) | PIM1MAPKAPK2GRM5ATMPTGS1 | |
| SCHEMBL5700322 | 0.72 | PIK3CG (0.50) | PIM1CYP2A6MAPKAPK2CCR1CCR5 | |
| SCHEMBL30898561 | 0.72 | ASIC3 (0.50) | PIM1MAPKAPK2CCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261172-B | Comprise the electronic installation of pyrimidine compound | E.I. Nemours DuPont (US) | 2016-05-04 | — | — | CN | disclosed |
| EP-2655339-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E.I. Du Pont De Nemours And Company (US) | 2013-10-30 | — | — | EP | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| US-20130256646-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-10-03 | — | — | US | disclosed |
| CN-103261172-A | Electronic device including a pyrimidine compound | DU PONT | 2013-08-21 | — | — | CN | disclosed |
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088192-A1 | ELECTRONIC DEVICE INCLUDING A PYRIMIDINE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-06-28 | — | — | WO | disclosed |