SCHEMBL1662224

SCHEMBL1662224

Clc1ccnc(-c2ccccc2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ASIC3 Q9UHC3 2/20 0.59
PIM1 P11309 1/20 0.58
CNR1 P21554 1/20 0.51
CCR1 P32246 1/20 0.48
CCR5 P51681 1/20 0.48
CCR8 P51685 1/20 0.48
ALDH1A1 P00352 2/20 0.48
MEN1 O00255 1/20 0.48
HPGD P15428 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MIF P14174 1/20 0.44
AURKA O14965 1/20 0.44
HSP90AA1 P07900 1/20 0.44
PRKACA P17612 1/20 0.44
ADORA2A P29274 1/20 0.44
KMO O15229 1/20 0.44
MAPK1 P28482 1/20 0.44
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3849043 0.88 PIM1 (0.53) ASIC3PIM1CNR1CCR1CCR5
SCHEMBL15947898 0.85 PIM1 (0.57) PIM1SMN1; SMN2KMONPC1
Hydrochloric Acid SCHEMBL15659071 0.83 PIM1 (0.55) PIM1SMN1; SMN2KMONPC1
SCHEMBL31074836 0.83 CCR1 (0.46) ASIC3PIM1CCR1CCR5CCR8
SCHEMBL31074875 0.82 PIM1 (0.48) ASIC3PIM1CNR1CCR1CCR5
SCHEMBL827247 0.81 CCR1 (0.48) PIM1CCR1CCR5CCR8ALDH1A1
SCHEMBL23487646 0.80 MAP4K4 (0.62) ASIC3PIM1CNR1ALDH1A1NPC1
SCHEMBL19786689 0.80 CYP2A6 (0.64) PIM1ALDH1A1HSP90AA1KMO
SCHEMBL30501156 0.80 MAP4K4 (0.62) ASIC3PIM1CNR1ALDH1A1NPC1
SCHEMBL18603218 0.80 MAP4K4 (0.62) ASIC3PIM1CNR1ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 238 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250338370-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2025-10-30 US disclosed
US-12439813-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPRATION (US) 2025-10-07 US disclosed
US-12435102-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-10-07 US disclosed
US-12408242-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2025-09-02 US disclosed
US-12127470-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-10-22 US disclosed
US-20240254139-A1 FUSED ISOXAZOLYL COMPOUNDS AS KAT6A INHIBITORS AURIGENE ONCOLOGY LTD (IN) 2024-08-01 US disclosed
US-20240138251-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2024-04-25 US disclosed
CN-117881677-A Fused isoxazolyl compounds as KAT6Aw inhibitors 奥瑞基尼肿瘤有限公司 2024-04-12 CN disclosed
EP-4341259-A1 FUSED ISOXAZOLYL COMPOUNDS AS KAT6A INHIBITORS Aurigene Oncology Limited (IN) 2024-03-27 EP disclosed
US-11910700-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 US disclosed
EP-1506962-A2 Nitrogen-containing aromatic heterocycles Eisai Co. Ltd. (JP) 2005-02-16 EP disclosed
EP-1415987-A1 NITROGENOUS AROMATIC RING COMPOUNDS Eisai Co., Ltd. (JP) 2004-05-06 EP disclosed
US-20040053908-A1 Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective EISAI R&D MANAGEMENT CO., LTD. (JP) 2004-03-18 US disclosed
CN-1473161-A Pyrazole compounds as protein kinase inhibitors ��̩��˹ҩ��ɷ����޹�˾ 2004-02-04 CN disclosed
CN-1469874-A Pyrazole compounds useful as protein kinase inhibitors ��̩��˹ҩ��ɷ����޹�˾ 2004-01-21 CN disclosed
CN-1469875-A Pyrazole compounds useful as protein kinase inhibitors ��̩��˹ҩ��ɷ����޹�˾ 2004-01-21 CN disclosed
EP-1318814-A2 TRIAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS Vertex Pharmaceuticals Incorporated (US) 2003-06-18 EP disclosed
EP-1317452-A1 PYRAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS Vertex Pharmaceuticals Incorporated (US) 2003-06-11 EP disclosed
WO-2002022608-A1 PYRAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-03-21 WO disclosed
WO-2002022602-A2 TRIAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-03-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12408242-B2 Heteroleptic iridium complexes as dopants JUND, DRD2, DRD1 ASIC3 3658/4885PIM1 945/4885CNR1 863/4885
US-20040053908-A1 Urea derivatives containing aromatic or heteroaromatic rings, useful as prophylactic or therapeutic agent for a disease for which angiogenesis inhibition is effective VEGFA, UACA, UTS2R ASIC3 4871/4885PIM1 3686/4885CNR1 804/4885
US-12439813-B2 Organic electroluminescent materials and devices OCIAD2, DRD2, OPRD1 ASIC3 2676/4885PIM1 4325/4885CNR1 615/4885
US-12435102-B2 Organic electroluminescent materials and devices OXER1, OCIAD1, OCIAD2 ASIC3 669/4885PIM1 3829/4885CNR1 2582/4885
US-20250338370-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 ASIC3 3658/4885PIM1 945/4885CNR1 863/4885
US-12127470-B2 Organic electroluminescent materials and devices SOD1, CLTB, L1CAM ASIC3 1471/4885PIM1 2899/4885CNR1 3084/4885
US-20240138251-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 ASIC3 3658/4885PIM1 945/4885CNR1 863/4885
US-20240254139-A1 FUSED ISOXAZOLYL COMPOUNDS AS KAT6A INHIBITORS KAT6A, KAT6B, KAT2A ASIC3 2704/4885PIM1 2588/4885CNR1 4624/4885
US-11910700-B2 Heteroleptic iridium complexes as dopants JUND, DRD2, DRD1 ASIC3 3658/4885PIM1 945/4885CNR1 863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.