Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956088 | 0.85 | HSD17B10 (0.42) | HSD17B10TSHRNPSR1HPGDGAA | |
| SCHEMBL5518084 | 0.71 | HSD17B10 (0.46) | HSD17B10ALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL9955516 | 0.69 | ALDH1A1 (0.46) | HSD17B10ALDH1A1NPSR1HPGDMAPT | |
| SCHEMBL11584471 | 0.68 | ALDH1A1 (0.52) | HSD17B10ALDH1A1TSHRNPSR1HPGD | |
| SCHEMBL71362 | 0.65 | NOTUM (0.48) | HSD17B10ALDH1A1TSHRNPSR1HPGD | |
| SCHEMBL5513393 | 0.65 | ALDH1A1 (0.63) | ALDH1A1TSHRNPSR1HPGDMAPT | |
| SCHEMBL27474631 | 0.63 | ALDH1A1 (0.61) | ALDH1A1TSHRNPSR1HPGDMAPT | |
| SCHEMBL30630152 | 0.63 | ALDH1A1 (0.61) | ALDH1A1TSHRNPSR1HPGDMAPT | |
| SCHEMBL27774758 | 0.63 | ALDH1A1 (0.47) | HSD17B10ALDH1A1TSHRNPSR1HPGD | |
| SCHEMBL4071297 | 0.63 | ALDH1A1 (0.47) | HSD17B10ALDH1A1TSHRNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655323-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO LABORATORIES LIMITED (IE) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012083953-A1 | INGENOL-3-ACYLATES III AND INGENOL-3-CARBAMATES | LEO PHARMA A/S (DK) | 2012-06-28 | — | — | WO | disclosed |