Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | POLQ | O75417 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14611610 | 0.81 | MME (0.41) | TDP1GAAIDO1HDAC1HDAC8 | |
| SCHEMBL271294 | 0.79 | NPSR1 (0.36) | MAOBMAOAKDM4ETDP1ATM | |
| SCHEMBL272016 | 0.79 | POLQ (0.49) | POLQHDAC1HDAC8EPHX2HDAC3 | |
| SCHEMBL269806 | 0.78 | PTGDR2 (0.35) | POLQKMT2AEPHX2 | |
| SCHEMBL270573 | 0.78 | HTT (0.44) | POLQGAAIDO1HTT | |
| SCHEMBL265536 | 0.77 | POLQ (0.59) | MAOBMAOAPOLQKDM4ETDP1 | |
| SCHEMBL31173765 | 0.77 | POLQ (0.59) | MAOBMAOAPOLQKDM4ETDP1 | |
| SCHEMBL13007589 | 0.76 | IDO1 (0.57) | ALDH1A1IDO1HTT | |
| SCHEMBL515164 | 0.76 | IDO1 (0.50) | MAOBMAOAPOLQKDM4ETDP1 | |
| Bromide SCHEMBL17260892 | 0.75 | IDO1 (0.56) | ALDH1A1IDO1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103313991-B | There is the substituted pyridines of weeding activity | BASF SE (DE) | 2016-02-10 | — | — | CN | disclosed |
| EP-2655381-B1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-2655381-B1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-8877683-B2 | Substituted pyridines having herbicidal activity | BASF SE (DE) | 2014-11-04 | — | — | US | disclosed |
| US-8877683-B2 | Substituted pyridines having herbicidal activity | BASF SE (DE) | 2014-11-04 | — | — | US | disclosed |
| US-8877683-B2 | Substituted pyridines having herbicidal activity | BASF SE (DE) | 2014-11-04 | — | — | US | disclosed |
| US-20130288899-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130288899-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2013-10-31 | — | — | US | disclosed |
| US-20130288899-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2013-10-31 | — | — | US | disclosed |
| EP-2655381-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2013-10-30 | — | — | EP | disclosed |
| CN-103313991-A | Substituted pyridines having herbicidal activity | BASF SE | 2013-09-18 | — | — | CN | disclosed |
| WO-2012084755-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012084755-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | BASF SE (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130288899-A1 | SUBSTITUTED PYRIDINES HAVING HERBICIDAL ACTIVITY | DDT, PNPO, CYP4X1 | MAOB 356/4885MAOA 328/4885POLQ 3582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.