Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3539843 | 0.89 | TSHR (0.48) | CYP4F2CYP4A11ALDH1A1LMNAMAPT | |
| SCHEMBL22922181 | 0.86 | CYP4F2 (0.59) | CYP4F2CYP4A11ALDH1A1LMNAMAPT | |
| Methyl 3-Phenylpropanoate SCHEMBL27447160 | 0.82 | TDP1 (0.66) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL1196988 | 0.81 | CYP4F2 (0.67) | CYP4F2CYP4A11MAPTTDP1EPHX2 | |
| Methyl 3-Phenylpropanoate SCHEMBL168711 | 0.80 | TDP1 (0.68) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL1196446 | 0.80 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1LMNAMAPT | |
| Water SCHEMBL27804228 | 0.79 | CYP4F2 (0.49) | CYP4F2CYP4A11ALDH1A1LMNAMAPT | |
| SCHEMBL5084479 | 0.79 | CA12 (0.47) | ALDH1A1LMNAMAPTHTTKMT2A | |
| SCHEMBL5187860 | 0.78 | CA12 (0.53) | CYP4F2CYP4A11ALDH1A1MAPTCA12 | |
| SCHEMBL2569441 | 0.78 | L3MBTL1 (0.55) | CYP4F2CYP4A11ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574322-A | Preparation method of difluoromethyl aromatic compound | 南京工业大学 | 2020-08-25 | — | — | CN | claimed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | claimed |
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | AUCKLAND UNIVSERVICES LIMITED (NZ) | 2012-09-06 | — | — | US | claimed |
| EP-2456435-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | The Board of Trustees of The Leland Stanford Junior University (US) | 2012-05-30 | — | — | EP | claimed |
| US-20110281821-A9 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC. (US) | 2011-11-17 | — | — | US | claimed |
| WO-2011011514-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-01-27 | — | — | WO | claimed |
| US-20100249067-A1 | Modulators of Mitotic Kinases | BIOGEN IDEC MA INC. (US) | 2010-09-30 | — | — | US | claimed |
| CN-101616920-A | The 1-H-pyrazolo (3,4b) pyrimidine derivatives and as the purposes of mitotic kinase conditioning agent | BIOGEN IDEC INC | 2009-12-30 | — | — | CN | claimed |
| EP-2108020-A2 | 1-H-PYRAZOLO[3,4B]PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | Biogen Idec MA, Inc. (US) | 2009-10-14 | — | — | EP | claimed |
| WO-2008094602-A2 | 1-H-PYRAZOLO (3,4B) PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES | BIOGEN IDEC MA INC. (US) | 2008-08-07 | — | — | WO | claimed |
| CN-111574322-A | Preparation method of difluoromethyl aromatic compound | 南京工业大学 | 2020-08-25 | — | — | CN | disclosed |
| CN-106661346-A | UV-curable coating composition with improved solar resistance | 老虎涂料有限责任及两合公司 | 2017-05-10 | — | — | CN | disclosed |
| EP-2456435-B1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | UNIV LELAND STANFORD JUNIOR (US) | 2015-06-24 | — | — | EP | disclosed |
| WO-2013062138-A1 | COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-02 | — | — | WO | disclosed |
| WO-2013027860-A1 | COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| US-4910109-A | Conductive support having a hydrophilic surface; then photoconductive insulation | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| CN-1037337-A | Substituted 2H-benzotriazole liquid mixtures | CIBA GEIGY AG (CH) | 1989-11-22 | — | — | CN | disclosed |
| EP-0038876-B1 | 2,6-DI-TERTIARY BUTYL PHENYL PENTAERYTHRITOL SPIRO BIS-PHOSPHITES ENHANCING THE STABILITY TO HEAT AND LIGHT OF SYNTHETIC RESINS, STABILIZER COMPOSITIONS COMPRISING PHENOLIC ANTIOXIDANTS AND SUCH PHOSPHITES, AND SYNTHETIC RESIN COMPOSITIONS CONTAINING THE SAME | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1984-10-10 | — | — | EP | disclosed |
| US-4469864-A | MAIN ABSORPTION NEAR 600 TO 700 NANOMETERS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-09-04 | — | — | US | disclosed |
| US-4389474-A | Thiopyrylium compounds and photoconductive compositions containing said compounds | FUJI PHOTO FILM CO., LTD. (JP) | 1983-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120225862-A1 | HETEROARYL BENZAMIDES, COMPOSITIONS AND METHODS OF USE | BRDT, NISCH, PAICS | CYP4F2 541/4885CYP4A11 2074/4885ALDH1A1 1336/4885 |
| US-20100249067-A1 | Modulators of Mitotic Kinases | BUB1, BUB1B, CDK1 | CYP4F2 3449/4885CYP4A11 1751/4885ALDH1A1 4063/4885 |
| US-20110281821-A9 | Modulators of Mitotic Kinases | BUB1, BUB1B, CDK1 | CYP4F2 3449/4885CYP4A11 1751/4885ALDH1A1 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.