Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9957862 | 0.92 | FFAR4 (0.43) | FFAR4FFAR1MAOBSLC2A1PDGFRA | |
| SCHEMBL3574032 | 0.87 | FFAR1 (0.41) | FFAR4FFAR1MAOBSLC2A1PDGFRA | |
| SCHEMBL9958958 | 0.86 | SLC2A1 (0.39) | FFAR4FFAR1MAOBSLC2A1PDGFRA | |
| SCHEMBL1397780 | 0.79 | CETP (0.37) | FFAR4SLC2A1S1PR1S1PR5MAPT | |
| SCHEMBL3570210 | 0.79 | FFAR1 (0.46) | FFAR4FFAR1MAOBSLC2A1PDGFRA | |
| SCHEMBL9957250 | 0.79 | S1PR1 (0.35) | SLC2A1S1PR1S1PR5 | |
| SCHEMBL3577779 | 0.78 | FFAR1 (0.43) | FFAR4FFAR1MAOBSLC2A1PDGFRA | |
| SCHEMBL1397565 | 0.76 | HCRTR1 (0.38) | SLC2A1MAPT | |
| SCHEMBL9958121 | 0.76 | LPAR1 (0.43) | SLC2A1KLK1 | |
| SCHEMBL1397787 | 0.75 | KMT2A (0.35) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |