Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576429 | 0.85 | LPAR1 (0.43) | LPAR1LPAR5TSHRSLC2A1HTR5A | |
| SCHEMBL3571746 | 0.83 | SLC2A1 (0.41) | LPAR1LPAR5TSHRSLC2A1HTR5A | |
| SCHEMBL3586145 | 0.78 | CNR1 (0.42) | LPAR1LPAR5SLC2A1LPAR2 | |
| SCHEMBL9957862 | 0.78 | FFAR4 (0.43) | SLC2A1KMT2AKLK1 | |
| SCHEMBL9958958 | 0.77 | SLC2A1 (0.39) | LPAR1LPAR5SLC2A1LPAR2 | |
| SCHEMBL3582130 | 0.76 | CNR1 (0.40) | LPAR1LPAR5SLC2A1HTR5A | |
| SCHEMBL9957377 | 0.76 | FFAR4 (0.41) | SLC2A1KLK1 | |
| SCHEMBL9958528 | 0.75 | F2 (0.39) | LPAR1LPAR5SLC2A1 | |
| SCHEMBL9957250 | 0.75 | S1PR1 (0.35) | LPAR1LPAR5SLC2A1KMT2ATDP1 | |
| SCHEMBL3587845 | 0.75 | LPAR1 (0.42) | LPAR1LPAR5SLC2A1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |