SCHEMBL9957765

SCHEMBL9957765

COc1ccc(F)cc1OS(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
TSHR P16473 2/20 0.46
POLB P06746 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 4/20 0.45
HTT P42858 1/20 0.45
USP2 O75604 1/20 0.45
NFE2L2 Q16236 1/20 0.44
PDE4B Q07343 1/20 0.44
PTGS2 P35354 1/20 0.43
FFAR1 O14842 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9958058 0.94 KDM4E (0.47) KDM4ETSHRPOLBMAPK1SMN1; SMN2
SCHEMBL3746820 0.82 PTGS2 (0.43) KDM4EPOLBHTTPTGS2ALDH1A1
SCHEMBL28755848 0.82 TSHR (0.52) KDM4ETSHRPOLBMAPK1SMN1; SMN2
SCHEMBL3751243 0.82 PTGS2 (0.37) KDM4ETSHRSMN1; SMN2HTTPTGS2
SCHEMBL166380 0.81 NFE2L2 (0.61) KDM4ETSHRPOLBMAPK1NFE2L2
SCHEMBL18472613 0.81 NFE2L2 (0.61) KDM4ETSHRPOLBMAPK1NFE2L2
SCHEMBL9958073 0.81 PDE4B (0.35) KDM4ETSHRPOLBMAPK1SMN1; SMN2
SCHEMBL9024638 0.81 PTGS2 (0.42) KDM4ETSHRSMN1; SMN2HTTPTGS2
SCHEMBL9958237 0.80 PDE4B (0.40) KDM4ETSHRPOLBMAPK1SMN1; SMN2
SCHEMBL31475556 0.79 CA1 (0.59) KDM4ETSHRPOLBMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029024-B2 Nonaqueous electrolyte solution and electrochemical element using same UBE INDUSTRIES, LTD. (JP) 2015-05-12 US disclosed
EP-2469638-B1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND ELECTROCHEMICAL DEVICE USING THE SAME UBE INDUSTRIES (JP) 2014-10-01 EP disclosed
US-20120189919-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME UBE INDUSTRIES, LTD. (JP) 2012-07-26 US disclosed
EP-2469638-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ube Industries, Ltd. (JP) 2012-06-27 EP disclosed
CN-102484280-A Nonaqueous Electrolyte Solution And Electrochemical Element Using Same UBE INDUSTRIES 2012-05-30 CN disclosed