Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 4/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 5/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166833 | 0.86 | P2RX3 (0.45) | P2RX3P2RX2GAAMGAMSI | |
| SCHEMBL13059718 | 0.76 | GAA (0.48) | P2RX3P2RX2GAAMGAMSI | |
| SCHEMBL21142303 | 0.76 | GAA (0.48) | P2RX3P2RX2GAAMGAMSI | |
| SCHEMBL12190518 | 0.76 | P2RX3 (0.48) | P2RX3P2RX2GAAMGAMSI | |
| SCHEMBL13085628 | 0.76 | P2RX3 (0.43) | P2RX3P2RX2GAAPDE3BPDE3A | |
| SCHEMBL29786811 | 0.73 | P2RX3 (0.38) | P2RX3P2RX2GAAMGAMSI | |
| SCHEMBL15927601 | 0.73 | P2RX3 (0.41) | P2RX3P2RX2GAAMGAMSI | |
| SCHEMBL171073 | 0.73 | POLB (0.46) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL22019566 | 0.72 | TAAR1 (0.50) | P2RX3P2RX2GAAPOLBGFER | |
| SCHEMBL9886089 | 0.72 | TAAR1 (0.50) | P2RX3P2RX2GAAPOLBGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468736-A1 | Synthesis of intermediates for preparing anacetrapib and derivates thereof | LEK Pharmaceuticals d.d. (SI) | 2012-06-27 | — | — | EP | disclosed |