Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.53 |
| ▸ | KDR | P35968 | 19/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | FPR1 | P21462 | 1/20 | 0.49 |
| ▸ | FPR3 | P25089 | 1/20 | 0.49 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958300 | 0.94 | MET (0.48) | METKDRAURKAFPR1FPR3 | |
| SCHEMBL9958865 | 0.93 | MET (0.53) | METKDR | |
| SCHEMBL9958118 | 0.90 | MET (0.51) | METKDRAURKAFPR1FPR3 | |
| SCHEMBL13861639 | 0.90 | MET (0.56) | METKDRAURKAFPR1FPR3 | |
| SCHEMBL9958154 | 0.88 | MET (0.52) | METKDRAURKAFPR1FPR3 | |
| SCHEMBL9958796 | 0.87 | MET (0.54) | METKDRAURKAFPR1FPR3 | |
| SCHEMBL9958585 | 0.85 | MET (0.43) | METKDR | |
| SCHEMBL4340635 | 0.85 | MET (0.60) | METKDR | |
| SCHEMBL4333803 | 0.84 | MET (0.56) | METKDRAURKAFPR1FPR3 | |
| SCHEMBL13861556 | 0.84 | MET (0.53) | METKDRAURKAFPR1FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |