Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 12/20 | 0.48 |
| ▸ | BRAF | P15056 | 4/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958079 | 0.93 | MET (0.53) | METKDR | |
| SCHEMBL13861610 | 0.90 | MET (0.55) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958797 | 0.87 | MET (0.51) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958300 | 0.87 | MET (0.48) | METKDR | |
| SCHEMBL9958536 | 0.86 | MET (0.49) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL14366534 | 0.85 | MET (0.55) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL9958118 | 0.83 | MET (0.51) | METKDR | |
| SCHEMBL4334017 | 0.83 | MET (0.59) | METCSF1RPDGFRBPDGFRAFLT3 | |
| SCHEMBL13861639 | 0.83 | MET (0.56) | METKDR | |
| SCHEMBL9958072 | 0.82 | MET (0.58) | METCSF1RPDGFRBPDGFRAFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |