Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | PRKCB | P05771 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 1/20 | 0.32 |
| ▸ | PRKCH | P24723 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.32 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.32 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968394 | 0.86 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3PRKD3 | |
| SCHEMBL21751436 | 0.84 | PRKD3 (0.44) | CHRM2CHRM1CHRM4CHRM3PRKD3 | |
| SCHEMBL15870316 | 0.84 | PRKD3 (0.44) | CHRM2CHRM1CHRM4CHRM3PRKD3 | |
| SCHEMBL789290 | 0.84 | PRKD3 (0.44) | CHRM2CHRM1CHRM4CHRM3PRKD3 | |
| SCHEMBL19696795 | 0.77 | CHRM2 (0.34) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL984906 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL789291 | 0.70 | METAP2 (0.30) | CHRM2CHRM1MEN1CYP2D6KMT2A | |
| SCHEMBL17279340 | 0.68 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL30891555 | 0.67 | CHRM2 (0.43) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL21771475 | 0.66 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468741-A1 | Novel quercetin derivatives, their preparation, pharmaceutical compositions containing them and their use | Bel/Novamann International s.r.o. (SK) | 2012-06-27 | — | — | EP | disclosed |