Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.51 |
| ▸ | KDR | P35968 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9958254 | 0.91 | MET (0.59) | METKDR | |
| SCHEMBL4337564 | 0.84 | MET (0.62) | METCYP3A4KDR | |
| SCHEMBL6031858 | 0.84 | MET (0.60) | METCYP3A4KDR | |
| SCHEMBL5711085 | 0.83 | MET (0.59) | METCYP3A4KDR | |
| SCHEMBL4337559 | 0.82 | MET (0.49) | METCYP3A4KDR | |
| SCHEMBL1136851 | 0.78 | MET (0.57) | METCYP3A4KDR | |
| SCHEMBL13861046 | 0.77 | KDR (0.64) | METKDR | |
| SCHEMBL1137024 | 0.76 | MET (0.73) | METCYP3A4 | |
| SCHEMBL4333424 | 0.76 | MET (0.86) | METCYP3A4KDR | |
| SCHEMBL4344016 | 0.75 | MET (0.60) | METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1719762-B1 | NOVEL PYRIDINE DERIVATIVE AND PYRIMIDINE DERIVATIVE (1) | EISAI R&D MAN CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |