Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PTPRB | P23467 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745450 | 0.82 | PTPRB (0.44) | ROCK2ROCK1MEN1NPC1RAB9A | |
| SCHEMBL1926329 | 0.69 | KCNT1 (0.46) | MEN1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL18114415 | 0.68 | SMN1; SMN2 (0.47) | POLBMAPTSMN1; SMN2KDM4EMAOA | |
| SCHEMBL3915895 | 0.67 | CYP1A2 (0.45) | FFAR1POLBMEN1KMT2APTPRB | |
| SCHEMBL1745058 | 0.66 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL3316286 | 0.64 | L3MBTL1 (0.55) | POLBMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18157938 | 0.63 | FDPS (0.38) | POLBMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1745448 | 0.63 | HDAC3 (0.51) | ROCK2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL11346806 | 0.62 | PTPRA (0.50) | POLBMEN1NPC1RAB9AKMT2A | |
| Methane SCHEMBL28852240 | 0.62 | CYP1A2 (0.49) | POLBNPC1RAB9ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698624-B1 | PHENYLPROPANOIC ACID DERIVATIVES | TAKEDA PHARMACEUTICAL (JP) | 2012-06-27 | — | — | EP | disclosed |