Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996068 | 0.89 | MAPK1 (0.51) | MEN1KMT2AALDH1A1FAAHMMP1 | |
| SCHEMBL995318 | 0.88 | MEN1 (0.45) | MEN1KMT2AALDH1A1FAAHHRH3 | |
| SCHEMBL995578 | 0.84 | HIF1A (0.48) | MEN1KMT2AHIF1AEPAS1L3MBTL1 | |
| SCHEMBL995576 | 0.84 | HIF1A (0.48) | MEN1KMT2AHIF1AEPAS1L3MBTL1 | |
| SCHEMBL995867 | 0.80 | L3MBTL1 (0.47) | MEN1KMT2AHIF1AEPAS1L3MBTL1 | |
| SCHEMBL16054126 | 0.79 | NPC1 (0.41) | KMT2AL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL995866 | 0.77 | PPARD (0.50) | MEN1KMT2AHIF1AEPAS1L3MBTL1 | |
| SCHEMBL995515 | 0.75 | KDM4E (0.54) | MEN1KMT2AHIF1AEPAS1L3MBTL1 | |
| SCHEMBL995513 | 0.75 | KDM4E (0.54) | MEN1KMT2AHIF1AEPAS1L3MBTL1 | |
| SCHEMBL16054821 | 0.74 | SMN1; SMN2 (0.41) | KMT2AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |