Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.42 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.42 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.42 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.42 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MDH1 | P40925 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL996067 | 0.89 | MAPK1 (0.49) | ALDH1A1MEN1KMT2ACACNA1G | |
| SCHEMBL995317 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ACACNA1GFAAH | |
| SCHEMBL995870 | 0.80 | MEN1 (0.46) | L3MBTL1ALDH1A1KDM4EPPARDPPARA | |
| SCHEMBL16054124 | 0.79 | KDM4E (0.39) | L3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL995866 | 0.76 | PPARD (0.50) | L3MBTL1ALDH1A1KDM4EPPARDPPARA | |
| SCHEMBL16054933 | 0.74 | HRH2 (0.41) | L3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL16054685 | 0.72 | SIGMAR1 (0.38) | L3MBTL1KMT2A | |
| SCHEMBL1000039 | 0.72 | SMN1; SMN2 (0.49) | L3MBTL1ALDH1A1KMT2AHRH3 | |
| SCHEMBL17384116 | 0.72 | SLC6A5 (0.45) | MEN1KMT2AFAAHSLC6A5 | |
| SCHEMBL27870547 | 0.72 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1KDM4EPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448920-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | Galderma Research & Development (FR) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011001089-A1 | NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-01-06 | — | — | WO | disclosed |